Why we selected this company:

Seroyal, a natural pharmaceutical company was founded in 1984.  Their products are based on scientific rationale using only the purest, highest quality, natural, raw ingredients available. Seroyal’s products are made with care and attention to every detail. To ensure product uniformity, each ingredient is accurately weighed, tested and precisely mixed. To retain the full healing properties of each component, all tablets are cold-pressed and a low pressure compressing process is used. This unique method does not involve the use of heat as is the standard practice in the industry. No lubricants or fillers are used during our encapsulation process whenever possible. They use the purest source of lubricant available, such as biodegradable vegetable cellulose, to maintain consistent capsule weight and content conformity.

Seroyal’s vegetable capsules are free of pesticides, preservatives and additives, tested by government-approved independent laboratories to ensure quick dissolution and disintegration. They guarantee that the disintegration time does not exceed 20 minutes from the time of ingestion for capsules, and 30 minutes for all their tablets. They regularly test their capsules and tablets to confirm weight variation and ingredient potency.

When manufacturing the Seroyal products, they follow the procedures outlined in the Good Manufacturing Practices. They ensure precision and objectivity during testing by contracting government-approved independent laboratories to assay and verify each ingredient for every product in each lot. They reconfirm each ingredient’s potency, weight variation, disintegration time and the absence of heavy metals, bacteria, E. coli, salmonella, yeasts, mold and other contaminants.

Why we selected this product:

Probiotics Hold Potential as a Treatment for Patients with Irritable Bowel Syndrome

In a systematic review and meta-analysis of randomized, controlled, blinded trials investigating the effects of probiotics in the treatment of patients with irritable bowel syndrome (IBS), the authors conclude that probiotics may improve symptoms of IBS. The authors included results from 20 trials with a total of 1,404 subjects in their analysis. Compared to placebo, pooled analysis found probiotic use to be associated with improvement in global IBS symptoms (pooled relative risk: 0.77) and reduction in abdominal pain (pooled RR=0.78). Given the fact that, according to the authors, IBS affects between 3-25% of the general population, the results of this meta-analysis offer hope that probiotics may be a safe and effective tool in the treatment of patients with IBS. However, the authors caution, "While our analyses suggest that probiotic use may be associated with improvement in IBS symptoms compared to placebo, these results should be interpreted with caution, given the methodological limitations of contributing studies." Additional research is warranted.

"Meta-analysis of probiotics for the treatment of irritable bowel syndrome," McFarland LV, Dublin S, World J Gastroenterol, 2008; 14(17): 2650-61. (Address: Department of Health Services Research and Development, VA Puget Sound Health Care System, Metropolitan Park West, 1100 Olive Way, Suite #1400, Seattle WA 98101, United States. E-mail: lynne.mcfarland@va.gov ).

Probiotics Protect Against Various Diarrhoeal Illnesses

In a review of studies related to the use of probiotics for the treatment of various gastrointestinal conditions, it was found that probiotics are effective in preventing and ameliorating various diarrhoeal illnesses in children and adults. Specifically, probiotics have been found to exert a protective effect against diarrhoeal illnesses including antibiotic-associated diarrhea in children and adults, and necrotizing enterocolitis in neonates. In order to enhance the anti-inflammatory effects of probiotics and restore colonization resistance of the commensal flora, current research is looking at the effects of combining probiotics with prebiotics. In addition, the use of new technologies is allowing for the elucidation of complex effects on gene expression in the gut, the probiotic, and bacterial pathogens. Finally, in order to treat gastrointestinal infection, novel therapeutic agents involving recombinant strains capable of binding bacterial toxins are being developed. This review suggests that probiotics have a very important role to play in preventing and helping to treat diarrhea/diarrhoeal illness. Further studies investigating strain-specific effects, dosing regimens, and contraindications are warranted.

"Effects of probiotics on the gastrointestinal tract," Snelling AM, Curr Opin Infect Dis, 2005; 18(5): 420-6. (Address: Department of Biomedical Sciences, University of Bradford, Bradford BD7 IDP, West Yorkshire, United Kingdom. E-mail: A.M.Snelling@Bradford.ac.uk ).

Benefits for the body:
For assisting and maintaining normal intestinal health

Interesting facts:
HMF Replete contains two strains of Lactobacillus acidophilus, Lactobacillus salivarius, Bifidobacterium bifidum and Bifidobacterium lactis along with fructo-oligosaccharides in high concentrations to ensure rapid establishment and dominance of probiotic cultures in the gastrointestinal tract, especially during and following antibiotic therapy and chemotherapy. Supplementation of Lactobacilli and Bifidobacteria will crowd out unwanted bacteria by repopulating the gastrointestinal tract. Lactobacillus salivarius, which triggers an anti-inflammatory response, has been demonstrated to be beneficial in inflammatory bowel diseases such as Crohn’s and ulcerative colitis. Major imbalances of friendly bacteria may result in severe abdominal discomfort, extreme fatigue and yeast infections. HMF Replete is an intensive probiotic replacement formula. It helps to recolonize the intestinal walls compromised during and following the use of antibiotics, chemotherapy and radiation. HMF Replete is indicated for acute and severe intestinal disturbances, dysbiosis, Irritable Bowel Syndrome, and for autoimmune conditions such as multiple sclerosis, AIDS, lupus and rheumatoid arthritis. Product ideal for vegans.

Ingredients:
Each Sachet (20 g) Contains (7 sachet total):
Lactobacillus acidophilus (two strains) 75 billion CFU
Bifidobacterium bifidum 12.5 billion CFU
Bifidobacterium lactis 12.5 billion CFU
Lactobacillus salivarius 30 billion CFU
Fructo-oligosaccharides (FOS) 10 g, May contain up to 170 billion CFU

*These statements have not been evaluated by the FDA.  If in doubt consult with a licensed naturopathic physician before use.  Physicians at Genesis Health Systems can be reached at 480.284.8155 and we are happy to consult with you about this product and helping you achieve optimal health.